Erethism is an abnormally high degree of irritability or sensitivity to stimulation of an organ or body part; abnormal excitement of a bodily organ or tissue
Erethism or erethism mercurialis is a symptom complex of mercury poisoning, presenting with excessive shyness, timidity and social phobia. This was common among hat makers of old England who used mercury to stabilize the wool in a process called felting. Hence the creation of the Mad Hatter by Lewis Carrol in the Alice stories.
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